2010 Holy Cross Men's Lacrosse Schedule & Results
| Overall | Pct. | Conf. | Pct. | Streak | Home | Away | Neutral |
| 5-10 | .333 | 1-5 | .167 | Lost 1 | 4-3 | 1-7 | 0-0 |
| Date | Opponent | Notes | Result | Time/Status | Links |
| Feb. 20 | at St. John's | L, 9-8 | Final | Box Score Recap | |
| Feb. 27 | at Yale | L, 14-7 | Final | Box Score Recap | |
| Mar. 2 | at Marist | L, 11-8 | Final | Box Score Recap | |
| Mar. 6 | Harvard | L, 9-7 | Final | Box Score Recap | |
| Mar. 9 | at Dartmouth | W, 13-8 | Final | Box Score Recap | |
| Mar. 13 | Colgate * | W, 9-8 | Final |
Box Score
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| Mar. 17 | at Hartford | L, 10-6 | Final | Box Score Recap | |
| Mar. 20 | at Navy * | L, 12-3 | Final | Box Score Recap | |
| Mar. 27 | at Lehigh * | L, 11-5 | Final | Box Score Recap | |
| Apr. 3 | Bucknell * | L, 11-2 | Final | Box Score Recap | |
| Apr. 6 | Vermont | W, 11-1 | Final |
Box Score
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| Apr. 10 | Lafayette * | L, 13-12 | Final - OT |
Box Score
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| Apr. 17 | Quinnipiac | W, 17-10 | Final |
Box Score
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| Apr. 20 | Bryant | W, 7-6 | Final | Box Score Recap | |
| Apr. 24 | at Army * | L, 13-10 | Final | Box Score Recap | |
| Home events in bold * Conference events # Exhibition events All times listed are Eastern Time | |||||









